In the Vernacular: Photography of the Everyday

This is the catalogue of the exhibition "In the Vernacular" at Boston University Art Gallery

Collective correlations in the giant dipole continuum of 12C

A continuum shell-model calculation based on the collective correlation model has been made for the giant resonance of 12C using the eigenchannel reaction theory. The low-lying negative-parity states of 11C and 11B have been taken into account by corehole coupling. Partial, total, and integrated photoabsorption cross sections are calculated for the region of the giant dipole resonance

Integrated technology: does it affect learner outcomes?

Because technology has become prevalent in classrooms, this study was undertaken to test whether the use of integrated technology, specifically computers and online activities, affects learner outcomes in a classroom setting. The outcomes from classes taught using integrated technology were compared to classes taught with traditional teaching strategies. Students in a 7th grade life-science class were given pre-tests and post-tests to determine their learning gains on the topics of genetics and photosynthesis. Each class was assigned different activities based on the subject. Each unit was covered in four 90 minute periods. When one set of classes was using integrated technology for a topic, the other set was using traditional methods of learning such as notes, discussions and book work. The integrated technology had no detectable effect on learner outcomes. There were no significant difference between mean learning gains and the different variables tested: class size, gender and teaching styles. However, there did appear to be a positive effect on the students’ behavior and attitude for learning the material. The technology-based methods did not detract from student learning. Over a more extended time frame, implementation of technology-based methods in the classroom may increase learning gains and/or foster increases in engagement and class attendance

Predictive Model for Design of a 3D Developmental Neurotoxicity Platform

Exposure to developmental toxins during gestation have been shown to be linked to neurological disorders such as epilepsy, schizophrenia, and dyslexia [1] . In this report we describe efforts that represent the ground work to develop a predictive neurotoxicity model to test developmental toxicity on early neuronal differentiation from drugs and toxins for human consumption or exposure. Developmental toxins are toxins that prevent stem cell differentiation into neurons by impacting neural development [2] . Currency technologies used to evaluate a compound\u27s potential as a developmental toxin are centered around culturing stem cells in a two-dimensional environment or exposing animal models to the compound. The stem cells are then monitored for changes in proliferation, differentiation, and death. These classes of experiments proved not only to be expensive, but also extremely time consuming and ineffective in some cases. These technologies do not accurately mimic the in vivo environment, which uses ECM proteins and cell-cell interactions to regulate cellular functions such as migration, apoptosis, and gene expression. Our predictive model would provide a more biologically accurate alternative of the human system compared to two-dimensional cell culture and animal models. Our model would further improve the quality and relevance of developmental neurotoxicity research, reduce the number of animal experiments and overall cost to evaluate the potential for a compound to act as a developmental toxin

Physics: The Ultimate Adventure

This book explains - in simple terms and with almost no mathematics - the physics behind recent and glamorous discoveries in Cosmology, Quantum Mechanics, Elementary Particles (e.g. Higgs bosons) and Complexity Theory. En route it delves into the historical landmarks and revolutions that brought about our current understanding of the universe. The book is written mainly for those with little scientific background, both college students and lay readers alike, who are curious about the world of modern physics. Unsolved problems are highlighted and the philosophical implications of the sometimes astounding modern discoveries are discussed. Along the way the reader gains an insight into the mindset and methodology of a physicist

Fine-Scale Variations in Eucritic Pyroxene FeO/MnO: Process vs. Provenance.

Most asteroidal igneous rocks are eucrite-like basalts and gabbros, composed mostly of ferroan low- and high-Ca pyroxenes and calcic plagioclase, plus smaller amounts of silica (most commonly tridymite), ilmenite, chromite, troilite, Ca-phosphate, metal and sometimes ferroan olivine. Eucrite-like mafic rocks are fragments of the crusts of differentiated asteroids, and most are likely from 4 Vesta

Transcript for Episode 37: Small d Democratizing: Opening Up the Montana Democratic Party

https://digitalcommons.mtech.edu/crucible_transcriptions/1036/thumbnail.jp

Basal Signalling Through Death Receptor 5 and Caspase 3 Activates p38 Kinase To Regulate Serum Response Factor (SRF)-Mediated Myod Transcription

We have previously reported that stable expression of a dominant negative Death Receptor 5 (dnDR5) in skeletal myoblasts results in decreased basal caspase activity and decreased mRNA and protein expression of the muscle regulatory transcription factor MyoD in growth medium (GM), resulting in inhibited differentation when myoblasts are then cultured in differentiation media (DM). Further, this decreased level of MyoD mRNA was not a consequence of altered message stability, but rather correlated with decreased acetylation of histones in the distal regulatory region (DRR) of the MyoD extended promoter known to control MyoD transcription. As serum response factor (SRF) is the transcription factor known to be responsible for basal MyoD expression in GM, we compared the level of SRF binding to the non-canonical serum response element (SRE) within the DRR in parental and dnDR5 expressing myoblasts. Herein, we report that stable expression of dnDR5 resulted in decreased levels of serum response factor (SRF) binding to the CArG box in the SRE of the DRR. Total SRF expression levels were not affected, but phosphorylation indicative of SRF activation was impaired. This decreased SRF phosphorylation correlated with decreased phosphorylation-induced activation of p38 kinase. Moreover, the aforementioned signaling events affected by expression of dnDR5 could be appropriately recapitulated using either a pharmacological inhibitor of caspase 3 or p38 kinase. Thus, our results have established a signaling pathway from DR5 through caspases to p38 kinase activation, to SRF activation and the basal expression of MyoD

Petrologic and oxygen-isotopic investigations of eucritic and anomalous mafic achondrites

The most common asteroidal igneous meteorites are eucrite-type basalts and gabbros rocks composed of ferroan pigeonite and augite, calcic plagioclase, silica, ilmenite, troilite, Ca-phosphate, chromite and Fe-metal. These rocks are thought to have formed on a single asteroid along with howardites and diogenites (HEDs). However, Northwest Africa (NWA) 011 is mineralogically identical to eucrites, but has an O-isotopic composition distinct from them and was derived from a different asteroid. Modern analyses with higher precision have shown that some eucrites have smaller O-isotopic differences that are nevertheless well-resolved from the group mean